Professional Self-Renewal

Self-renewal and differentiation

The adult human heart has limited regenerative capacity and, theref fore, functional restoration of the damaged heart presents a great challenge. Despite the progress achieved in the pharmacological and surgical treatment of degenerative myocardial diseases, they are still considered a major cause of morbidity and mortality in the western world. Repopulation of the damaged heart with cardiomyof...

Self-Renewal of Stem Cells

Asymmetric division is one of the most fundamental characteristics of adult stem cells , which ensures one daughter cell maintains stem cell status and the other daughter cell becomes committed to differentiation. New data emerged recently that allow us to conclude that asymmetric division has another important aspect: it enables self-maintenance of stem cells.

Licensure and Professional Certification Renewal Requirements: 2017 Survey Results.

Understanding Professional Self-Regulation

In the course of daily life, people routinely come together to make business transactions in which they buy and sell products and services ranging from groceries to dental care. When making these transactions, some people may be disadvantaged as compared to others, due an imbalance of information and knowledge. While the average person will be able to determine when a piece of fruit has spoiled...

Controlling Pre-leukemic Thymocyte Self-Renewal

T cell acute lymphoblastic leukemia (TALL) develops in a multistep process whereby thymic progenitor cells gradually accumulate genetic and epigenetic changes, eventually leading to fully transformed immature lymphoblasts. Aberrant activation of transcription factor oncogenes is considered a core component of the oncogenic program that drives malignant T cell transformation. For example, the TA...